As St. Louis approaches its 250th birthday, historian Kevin Fernlund will speak on its dynamic and fascinating science history. The professor of history at the University of Missouri–St. Louis will give the keynote lecture, “St. Louis: Gateway to Infinity,” for Field Notes, a celebration of science and art in Grand Center. The free lecture will begin at 10:30 a.m. Oct. 19 in the St. Louis Public Radio auditorium in UMSL at Grand Center, 3651 Olive St. in St. Louis.